Abstract Background Although genes play a key role in many complex diseases, the specific genes involved in most complex diseases remain largely unidentified.Their discovery will hinge on the identification of key sequence variants that are conclusively associated with disease.While much attention has been focused on variants in protein-coding DNA,
Purpose: The paper develops a systematic overview of business Puzzles model portfolios and links it to the diversification literature.It conceptualizes the firm as consisting of multiple, different business models, with the purpose of advancing the structural, organizational and strategic understanding of business models and corporations.Design: Th
One of the causes of non-tumor related hyperprolactinemia is taking a medications.Physicians of various specialties, such as cardiologists, gastroenterologists, endocrinologists, and neurologists, encounter hyperprolactinemia as a side effect of drug therapy in their practice, but it is most often observed in the practice of a psychiatrist when tre
Background: The COVID-19 is a pandemic viral infection with a high morbidity rate, leading to many worldwide deaths since the end of 2019.The RBD (Receptor Binding Domain) of SARS-CoV-2 through its spike utilizes several host molecules to enter host cells.One of the most important ones is the angiotensin-converting enzyme 2 (ACE2), an enzyme normal